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WHO Reclassifies Hepatitis D as Cancerous, Urges Stronger Prevention Measures

Co-infection with hepatitis B greatly increases risk of cirrhosis and liver cancer

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WHO Reclassifies Hepatitis D as Cancerous, Urges Stronger Prevention Measures
  • The World Health Organization (WHO) has recently reclassified hepatitis D as cancerous, highlighting the urgent need to prevent viral hepatitis, which is emerging as a major public health crisis worldwide.
  • Hepatitis D is a severe liver infection caused by the hepatitis D virus (HDV), an incomplete virus that requires hepatitis B virus (HBV) for replication.
  • It affects only those already infected with hepatitis B, either simultaneously or subsequently, and significantly increases the risk of liver cirrhosis and cancer.
  • Compared to hepatitis B alone, hepatitis B–D co-infection carries a two- to six-fold higher risk of liver cancer.
  • Like hepatitis B and C, HDV spreads through injections and blood transfusions, mother-to-child transmission, and sexual contact.
  • Universal hepatitis B vaccination indirectly prevents hepatitis

Vaccination schedules may include:

  • Birth, 1 month, and 6 months
  • Birth, 6 weeks, and 14 weeks
  • 6, 10, and 14 weeks
  • In catch-up cases: 0, 1, and 6 months. Adults in high-risk groups are advised to take three doses — the second after one month and the third six months later.
  • WHO’s reclassification underscores the need for stronger vaccination drives and public health measures to curb the growing hepatitis burden.

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