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Nitric Oxide

A study published in Science Translational Medicine found that high-dose inhaled nitric oxide reduced drug-resistant Pseudomonas in a large-animal ICU model.

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Nitric Oxide

Why is it in the news?

→ A study published in Science Translational Medicine found that high-dose inhaled nitric oxide reduced drug-resistant Pseudomonas in a large-animal ICU model.

→ The research highlights its potential medical use against resistant infections.



Category: S&T

Important Points

  • Nitric oxide exists in gaseous state and is composed of one nitrogen and one oxygen atom.
  • First prepared around 1620 by Jan Baptista van Helmont and studied in 1772 by Joseph Priestley.
  • Formed through nitrogen oxidation. Can be created during lightning or commercially by burning ammonia. It is a colorless, toxic and non-combustible gas that accelerates burning of combustible materials. Found naturally in the environment and within parts of the human body.
  • Plays important chemical signalling roles in humans and animals. Transmits signals in cardiovascular, nervous and immune systems.
  • Synthesized from amino acid L-arginine with nitric oxide synthase.
  • Helps regulate blood pressure by dilating blood vessels and acts as a neurotransmitter.
  • Generated by automotive engines and thermal power plants and acts as air pollutant.


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